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Rheumatoid Arthritis

A new experimental drug effectively relieves swelling and pain in patients and it could be a breakthrough treatment.

Dolores Mershon is a schoolteacher. For the past 25 years she has corrected
papers even with a severe case of Rheumatoid Arthritis.

Dolores Mershon/Rheumatoid Arthritis patient - "I lived with this inflammation for many, many years and it destroyed a lot of my joints."

But now a new drug called Enbrel offers more hope to people like Dolores.

Dr. C. Michael Franklin/Rheumatologist - "You can measure very dramatic reductions in that swelling. and that swelling's what causes joint damage."

Enbrel works on a substance called Tumor Necrosis factor or TNF. in patients with Rheumatoid Arthritis, like Dolores, TNF builds up in the joints. That leads to swelling and inflammation and destroys the joints. Enbrel makes the TNF inactive.

Dr. Michael Franklin -"And by making it inactive, it controls the inflammation."

It appears to be safe.

Dr. Michael Franklin - "It's very targeted, it doesn't damage any cells."

And easy on the patient, while it does have to be injected, it only has to be taken twice a week.

Dolores Mershon - "I just think it's absolutely fantastic, especially if people will get it early."

dr. micahel franklin - "And it's likely that if we can get people treated earlier that we'll prevent the need for joint replacements and a lot of the disability that can go along with Rheumatoid Arthritis."

It could mean that people like Dolores won't face a lifetime of pain.

Enbrel is still considered experimental. But the Food and Drug Administration is rushing thru it's usual approval process required for a new drug to possibly get it on the market.

For information on Enbrel call 800-immunex or visit the manufacturer's web site
at www.immunex.com/products/html/enbreldefault.html

For general information on Rheumatoid Arthritis, contact the Arthritis Foundation at 800-283-7800 or contact their web site at www.arthritis.org.


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